A Unique Magnetic Resonance Imaging Feature of Glioblastoma Multiforme: the ‘Pseudopalisade’ Sign  

Oleh:

Huang, BC ; Geng, DY ; Zee, CS

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of International Medical Research vol. 38 no. 02 (Mar. 2010), page 686-693.
Topik: glioblastoma multiforme (GBM); glioma; magnetic resonance imaging; pseudopalisading; pseudopalisade sign

Ketersediaan

Perpustakaan FK Nomor Panggil: J11.K.2010.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

This study was designed to investigate the unique magnetic resonance imaging (MRI) appearance of histopathologically-proven glioblastoma multiforme (GBM) with pseudopalisade necrosis and to assess its value for grading gliomas and providing a differential diagnosis. The study included 169 patients with intracranial masses who underwent surgery and had a proven histopathological diagnosis: 50 with GBM, 77 with gliomas (46 grade II and 31 grade III) and 42 with other intracranial masses (20 metastases, 14 lymphomas and eight abscesses). All patients underwent pre-operative brain MRI including post-contrast T1-weighted imaging. The presence of the ‘pseudopalisade’ sign on post-contrast T1-weighted images was compared among the different types of brain mass. The frequency of the ‘pseudopalisade’ sign in GBMs (94.00%) was significantly higher than that seen in grade II and III gliomas (11.69%) and other intracranial masses (7.14%). The ‘pseudopalisade’ sign on post-contrast T1-weighted images was useful for grading gliomas and for differentiating GBM from other brain masses.

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