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ArtikelMesangial Glomerulonephritis and Transient SLE Manifestations in An Adolescent with Dermatomyositis  
Oleh: Picco, P. ; Gattomo, M. ; Barbano, GC ; Trivelli, A. ; Pistoia, V. ; Buoncompagni, A.
Jenis: Article from Journal
Dalam koleksi: Lupus vol. 6 no. 1 (1997), page 72-73.
Topik: Mesangial Glomerulonephritis; SLE
Fulltext: 72.full.pdf (175.78KB)
Isi artikelSS, 16 year-old, was admitted because of severe muscle weakness, fever, mucositis and periorbital and skin rash. At physical examination we found (i) truncal and symmetrical proximal muscle weakness; (ii) swelling of eyelids, heliotrope hue to the upper eyelids and maculo-papular rash over the interphalangeal joints and knees (Gottron’s nodules); (iii) aphtous stomatitis. A consistent increase of the muscle enzyme plasma concentration (CK 15.800 UI/L, nv < 140 UI/L, aldolase 59.0 UI/L nv < 10 UI/L, LDH 1910 UI/L nv < 230 UI/L, ALT 565 UI/L nv 45 UI/L, ASP 275 UI/L nv 45 UI/L) was found. Acute phase reactants were negative. Blood cell count revealed leukopenia (WBC 4.290 mmc, neutrophils 3.200 mmc, lymphocytes 700 mmc): no morphological abnormalities of leukocytes were present at smear examination. Platelet count was decreased ( 114.000 mmc).
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