Catastrophic Haemorrhage in A Case of Paediatric Primary Antiphospholipid Syndrome and Factor II Deficiency  

Oleh:

Hudson, N. ; Duffy, CM ; Rauch, J. ; Paquin, JD ; Esdaile, JM

Jenis: Article from Journal
Dalam koleksi: Lupus vol. 6 no. 1 (1997), page 68-71.
Topik: Primary Antiphospholipid Syndrome; Factor II Deficiency; Antiphospholipid Antibodies; Haemorrhage
Fulltext: 68.full.pdf (341.33KB)

Isi artikel

The first case of primary antiphospholipid syndrome associated with recurrent life-threatening haemorrhages, due to the coexistence of acquired prothrombin deficiency, is described. Attention is drawn to the difficulty in diagnosing this situation, and therapeutic options are reviewed. Evidence is presented that implicates prothrombin as the protein cofactor for this lupus anticoagulant.

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