Screening for Colorectal Cancer  

Oleh:

Lieberman, David A.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 361 no. 12 (Sep. 2009), page 1179-1187.
Topik: Colorectal Cancer

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2009.05 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Colorectal cancer is the second leading cause of death from cancer in the United States. This year, it is estimated that there will be 147,000 newly diagnosed cases of colorectal cancer and nearly 50,000 deaths associated with this disease.1 The age-adjusted incidence of colorectal cancer in the United States is 61.2 cases per 100,000 population among men and 44.8 per 100,000 population among women. These rates have been slowly decreasing since 1985. There is considerable evidence that screening of asymptomatic persons who are at average risk can detect cancers at an early and curable stage, resulting in a reduction in mortality. Furthermore, some screening tests may also detect cancer-precursor lesions, which, if removed, may result in a reduced incidence of colorectal cancer. There are several different screening tests, each with advantages and limitations (Table 1Table 1Advantages, Limitations, and Uncertainties of Screening Tests to Detect Colorectal Cancer.); differences among strategies in terms of the sensitivity and specificity of the tests, their complexity, and the associated risk complicate the process of informed decision making.

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