Detail Structure-Function Relationships of Anti-DNA Antibodies   Oleh:  Kalsi, J.K. ; Martin, A.C.R. ; Isenberg, D.A. Jenis: Article from Journal Dalam koleksi: Lupus vol. 4 no. 4 (1995), page 245-248. Topik: Anti-DNA Antibodies Fulltext: Lupus-1995-Kalsi-245-8.pdf (457.77KB) Isi artikel Antibodies to double-stranded DNA (dsDNA) are a serological marker for systemic lupus erythematosus (SLE). Their generation remains one of the most enigmatic features of SLE. High affinity antibodies are generated to nucleic acids, which have repeatedly been shown to be poorly immunogenic. The initial trigger for the production of anti- DNA antibodies therefore remains unknown, although various suggestions have been made (reviewed in ref. 1). Clinically, anti-dsDNA antibodies often reflect disease activity2 and, in particular, are associated with the presence of active lupus nephritis. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

Copyright © 2006, 2007 Unika Atma Jaya, all rights reserved