Detail Induction of Anticardiolipin Antibody and/or Lupus Anticoagulant in Rabbits by Immunization with Lipoteichoic Acid, Lipopolysaccharide and Lipid A   Oleh:  Gotoh, M ; Matsuda, J Jenis: Article from Journal Dalam koleksi: Lupus vol. 5 no. 6 (1996), page 593-597. Topik: Anticardiolipin Antibody; Lupus Anticoagulant; Microorganism Derivative Fulltext: 593.full.pdf (364.68KB) Isi artikel It still remains unclear how anti-phospholipid antibody develops in a specific patient group, however, it is possible that certain microorganism(s) may cause anti-cardiolipin antibody (aCL) development since aCL is frequently detected in patients with Treponema pallidum (TP) and/or other infectious diseases. Accordingly, we conducted an investigation to clarify whether or not anticardiolipin antibody (aCL) and/or lupus anticoagulant (LA) can be induced in rabbits by immunization with Gram-positive or -negative microorganism derivatives, such as lipoteichoic acid, lipopolysaccharide and lipid A. We detected the induction of SLE type-aCL (2GP&I-bdeepetndaen;t) and LA in some rabbits immunized with lipid A and lipoteichoic acid, thereby suggesting that some microorganisms may contribute to even the production of pathogenic (SLE-type) antiphospholipid antibody. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

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