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ArtikelCase Report Late Development of Anti-La/SS-B Antibodies in A Patient with Sjogren’s Syndrome and High Titer Anti-Ro/SS-A Antibodies  
Oleh: Satoh, M ; Hamilton, KJ ; Langdon, JJ ; Akizuki, M. ; Nakayama, S ; Reeves, WH ; Homma, M
Jenis: Article from Journal
Dalam koleksi: Lupus vol. 5 no. 3 (1996), page 337-339.
Topik: Anti-La Antibodies; Anti-Ro Antibodies; Sjogren’s Syndrome; Antinuclear Antibodies
Fulltext: 337.full.pdf (278.23KB)
Isi artikelThe frequent coexistence of anti-Ro and anti-La autoantibodies is well described, however, there is little evidence of sequential development of these two autoantibodies. We report a case of typical Sjogren’s syndrome with high titer anti-Ro antibodies, who subsequently developed anti-La antibodies later in the course. This case suggests that the anti-La antibodies may actually follow the anti-Ro antibodies in some cases as hypothesized in the concept of linked set of autoantibodies, analogous to development of anti-Sm in certain anti-nRNP antibody positive SLE patients and animal models.
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