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ArtikelLong Term Follow-Up of Children with Mixed Connective Tissue Disease  
Oleh: Mier, R ; Ansell, B ; Hall, MA ; Hasson, N ; Levinson, J ; Lovell, D ; Passo, M ; Rennebohm, R ; Woo, P
Jenis: Article from Journal
Dalam koleksi: Lupus vol. 5 no. 3 (1996), page 221-226.
Topik: Mixed Connective Tissue Disease; Overlap Syndrome; Undifferentiated Connective Tissue Disease; RNP Antibodies
Fulltext: 221.full.pdf (513.67KB)
Isi artikelMixed connective tissue disease (MCTD) is characterized by features of more than one of the rheumatic disorders with antinuclear antibodies in a speckled pattern and with antibodies to nuclear ribonucleoprotein (nRNP). MCTD is uncommon in children and longterm follow-up studies in children are infrequently reported. A retrospective review of clinical experience at five pediatric rheumatology centers provided 11 patients who met the following inclusion criteria: (1) Kasukawa’s criteria for M1;CTD (2) presentation younger than 18th birthday; (3) greater than five years of follow-up; (4) completion of data collection form. The widely varying outcomes of these 11 children with MCTD on long-term follow-up may lend doubt that this is a unique and distinctive rheumatologic disorder.
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