The Graft-Versus-Tumor Effect in Pediatric Malignancy  

Oleh:

Fry, Terry J. ; Willasch, Andre ; Bader, Peter

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 57 no. 01 (Feb. 2010), page 67-81.
Topik: Graft-versus-host disease; Allogeneic hematopoietic stem cell transplantation; Graft-versus-tumor effect; Graft-versus-host reaction; Graft-versus-leukemia

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.2010.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Because severe forms of the graft-versus-host reaction directed against normal tissues (also termed graft-versus-host disease [GVHD]) also contribute to morbidity and mortality following allogeneic hematopoietic stem cell transplantation, major efforts have focused on strategies to separate GVHD from the potentially beneficial immune reactivity against tumor (also called the graft-versus-tumor [GVT] effect). This article focuses on the data supporting the contribution of the GVT effect to cure of malignancy, what is known about the biology of the GVT reaction, and, finally, strategies to manipulate the GVT effect to increase the potency of HSCT.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali