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Cardiac Diastolic Dysfunction and Metabolic Syndrome in Young Women After Placental Syndrome
Oleh:
Zandstra, Mirjam
;
Stekkinger, Eva
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
Obstetrics and Gynecology vol. 115 no. 01 (Jan. 2010)
,
page 101-108.
Topik:
OBSTETRI GINEKOLOGI
Ketersediaan
Perpustakaan FK
Nomor Panggil:
O01.K.2010.01
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
OBJECTIVE: To estimate whether women with a recent history of a placental syndrome and concomitant metabolic syndrome have reduced cardiac diastolic function. METHODS: In this cohort study, women with a history of a placental syndrome were included. We assessed body mass index, blood pressure, fasting serum lipids, glucose and insulin levels, and 24-hour urinary protein and albumin output after an interval of at least 6 months postpartum. Cardiac diastolic function was assessed by echocardiography. RESULTS: Metabolic syndrome was found in 22% of the women evaluated. Diastolic dysfunction was seen in 24% of the women with the metabolic syndrome compared with 6.3% in those without (odds ratio 4.77, 95% confidence interval 2.18–10.41; adjusted odds ratio 6.09, 95% confidence interval 2.64–14.04). Univariable analysis showed that all the constituents of the metabolic syndrome related to diastolic dysfunction. CONCLUSION: In women with a history of placental syndrome complicating pregnancy, the presence of metabolic syndrome increases the risk of cardiac diastolic dysfunction fourfold.
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