Circulating Leptin: a Marker of Health in Female Students  

Oleh:

Kondo, T. ; Yoshida, A. ; Okada, R. ; Kanda, T. ; Kobayashi, I. ; Murakami, M.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of International Medical Research vol. 30 no. 02 (Mar. 2002), page 109-115.
Topik: Leptin

Ketersediaan

Perpustakaan FK Nomor Panggil: J11.K.01-04.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

We studied the relationship between serum leptin concentration and lifestyle factors in female nursing students. Serum leptin was estimated by radio­immunoassay and the correlation between these concen­trations with serum lipids, physical fitness and Health-promoting Lifestyle Profile score was investigated. A total of 247 students took part in the study: mean age, 19.0 +/- 2.0 years; mean body mass index (BMI), 21.7 +/- 2.9 kg/m2; and mean serum leptin concentration, 10.8 +/- 11.5 ng/ml. Serum leptin was positively correlated with BMI, systolic and diastolic blood pressure, total cholesterol and serum triglyceride. Serum leptin level concentration inversely correlated with physical fitness score and lifestyle score. When the subjects were grouped according to BMI, the high-BMI group (BMI: more than or equal to 24 kg/m2; n = 40) showed significantly lower fitness and lifestyle scores than the low-BMI group (BMI less than or equal to 20 kg/m2; n = 70). Higher leptin, blood pressure, total cholesterol and triglyceride were seen in high-BMI compared with low-BMI subjects. We suggest that leptin is a useful marker for monitoring good health and may be useful as a motivational aid towards achieving and maintaining a healthy lifestyle.

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