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Interaksi Obat yang Penting di Klinik
Oleh:
Nah, Yasavati Kurnia
Jenis:
Article from Bulletin/Magazine
Dalam koleksi:
Meditek vol. 15 no. 39 (Jan. 2007)
,
page 20-30.
Topik:
Drugs interaction
;
multiple drugs therapy
;
pharmacodynamic
;
pharmacokinetic
Ketersediaan
Perpustakaan FK
Nomor Panggil:
MM56.01 (M58.K.2004)
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Many drug interactions can be predicted if pharmacodynamic effects, pharmacokinetics properties and other mechanisms of action of the interacting agents are known. The effect of one drug can be increased or decreased or a quite new effect produced by the previous, concurrent or subsequent administration of another. The increasing number of drugs available and the increasing use of multidrug therapeutic regimens enhace the potential for drug interaction. The most obvious interactions are those producing altered pharmacokinetics of oral anticoagulants, antidiabetic drugs, cardiac glycosides, nonsedating antihistamine, benzodiazepines, immunosuppressant and cytotoxic drugs. These drugs have low therapeutic ratio and an altered response may be potentially lethal.
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