Susceptibility Patterns of Salmonella typhi and Salmonella paratyphi A to Ciprofloxacin, Levofloxacin, Chloramphenicol, Tetracycline, Ceftriaxone and Trimethoprim-Sulfamethoxazole in Jakarta 2002-2008  

Oleh:

Moehario, Lucky Hartati ; Tjoa, Enty ; Kiranasari, Ariyani

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Cermin Dunia Kedokteran vol. 36 no. 05/171 (Aug. 2009), page 328.
Topik: Salmonella typhi; Salmonella paratyphi A; Ciprofloxacin; Levofloxacin; Chloramphenicol; Tetracycline; Ceftriaxone and Trimethoprim-Sulfamethoxazole
Fulltext: Lucky H Moehario, Enty, Ariyani Kiranasari.pdf (1.36MB)

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Perpustakaan FK Nomor Panggil: C04.K.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Enteric fever remains a global problem partcularly in countries with poor hygiene. Predominant etiologies in Indonesia are Salmonella enterica subsp. enterica serovar Typhi (S. typhi) and Salmonella enterica subsp. enterica serovar Paratyphi A (S. paratyphi A). CDC Indonesia reported the prevalence of Typhoid Fever was 358-810/100,000 population in 2007, with 64% of the disease was found in people aged 3-19 years, and mortality rate varies from 3.1-10.4% among hospitalized patients. In the last two decades, the worldwide emergence of multidrug resistant (MDR) strains of S. typhi had been reported. These strains were resistant to Chloramphenicol, Trimethoprim-Sulfamethoxazole and Ampicillin. Moreover, Nalidixic acid-resistant strains exhibiting reduced susceptibility to Ciprofloxacin had become endemic in Indian subcontinent, Unites States, United Kingdom and also in other developed countries in 1997, reflecting the emergence of a global problem. This study described susceptibility patterns of S. typhi and S. paratyphi A to antibiotics generally used by clinicians to treat suspected or confirmed Typhoid Fever in the last six years in Jakarta.

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