Detail Microreview: Biological systems of the host cell involved in Agrobacterium infection (in Cellular Microbiology 9(1)) Bibliografi Author: Citovsky, Vitaly ; Kozlovsky, Stanislav V. ; Lacroix, Benoit ; Zaltsman, Adi ; Dafny-Yelin, Mery ; Vyas, Shachi ; Tovkach, Andriy ; Tzfira, Tzvi Topik: Bacterial virulence machinery; Genetic transformation; Plant cell surface receptors; Agrobacterium attachment; Molecular motors; Intracellular movement; T-complex; Nuclear import; Chromatin targeting; Targeted proteolysis; T-DNA uncoating; DNA repair; T-DNA integration; Plant immunity; T-DNA expression Bahasa: (EN )     Penerbit: Blackwell Publishing     Tempat Terbit: Malden    Tahun Terbit: 2007     Jenis: Article - diterbitkan di jurnal ilmiah internasional Fulltext: j.1462-5822.2006.00830.x.pdf (460.71KB; 0 download) [Informasi yang berkaitan dengan koleksi ini di internet] Abstract Genetic transformation of plants by Agrobacterium, which in nature causes neoplastic growths, represents the only known case of trans-kingdom DNA transfer. Furthermore, under laboratory conditions, Agrobacterium can also transform a wide range of other eukaryotic species, from fungi to sea urchins to human cells. How can the Agrobacterium virulence machinery function in such a variety of evolutionarily distant and diverse species? The answer to this question lies in the ability of Agrobacterium to hijack fundamental cellular processes which are shared by most eukaryotic organisms. Our knowledge of these host cellular functions is critical for understanding the molecular mechanisms that underlie genetic transformation of eukaryotic cells. This review outlines the bacterial virulence machinery and provides a detailed discussion of seven major biological systems of the host cell–cell surface receptor arrays, cellular motors, nuclear import, chromatin targeting, targeted proteolysis, DNA repair, and plant immunity – thought to participate in the Agrobacterium-mediated genetic transformation. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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