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Seroprevalence of Hepatitis C Virus Infection and Evaluation of Serum Aminotransferase Levels among Haemodialysis Patients in Izmir, Turkey
Oleh:
Olut, A.I.
;
Ozsakarya, F.
;
Dilek, M.
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
The Journal of International Medical Research vol. 33 no. 06 (Nov. 2005)
,
page 641-646.
Topik:
Serum aminotransferases
;
haemodialysis
;
hepatitis C virus
;
viraemia
Ketersediaan
Perpustakaan FK
Nomor Panggil:
J11.K.05-06.01
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
The seroprevalence of hepatitis C virus (HCV) infection was investigated among haemodialysis (HD) patients. Mean serum aminotransferase levels were also compared over 3 months in HCV-seropositive patients with and without viraemia, as well as in HCV-seronegative HD patients and HCV-seropositive, non-uraemic, viraemic patients. Seroprevalence of HCV infection was 19% among the 437 HD patients tested. Of the 61 HD HCV-seropositive, hepatotoxic medication- and alcohol-free patients, 38 (62%) were found to be viraemic, using quantitative HCV-RNA, on at least one occasion. Mean serum aminotransferase levels were significantly higher in viraemic HD patients (compared with non-viraemic patients), suggesting that HCV-RNA positivity is an important predictor of increased enzyme activity in these patients. As expected, aminotransferase levels in HCV-seropositive HD patients tended to be lower than levels in HCV-seropositive non-uraemic patients.
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