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ArtikelSeroprevalence of Hepatitis C Virus Infection and Evaluation of Serum Aminotransferase Levels among Haemodialysis Patients in Izmir, Turkey  
Oleh: Olut, A.I. ; Ozsakarya, F. ; Dilek, M.
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of International Medical Research vol. 33 no. 06 (Nov. 2005), page 641-646.
Topik: Serum aminotransferases; haemodialysis; hepatitis C virus; viraemia
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: J11.K.05-06.01
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
    Lihat Detail Induk
Isi artikelThe seroprevalence of hepatitis C virus (HCV) infection was investigated among haemodialysis (HD) patients. Mean serum aminotransferase levels were also compared over 3 months in HCV-seropositive patients with and without viraemia, as well as in HCV-seronegative HD patients and HCV-seropositive, non-uraemic, viraemic patients. Seroprevalence of HCV infection was 19% among the 437 HD patients tested. Of the 61 HD HCV-seropositive, hepatotoxic medication- and alcohol-free patients, 38 (62%) were found to be viraemic, using quantitative HCV-RNA, on at least one occasion. Mean serum aminotransferase levels were significantly higher in viraemic HD patients (compared with non-viraemic patients), suggesting that HCV-RNA positivity is an important predictor of increased enzyme activity in these patients. As expected, aminotransferase levels in HCV-seropositive HD patients tended to be lower than levels in HCV-seropositive non-uraemic patients.
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