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Transcription Regulation Through Promoter-Proximal Pausing of RNA Polymerase II
Oleh:
Core, Leighton J.
;
Lis, John T.
Jenis:
Article from Bulletin/Magazine
Dalam koleksi:
SCIENCE (keterangan: ada di Proquest) vol. 319 no. 5871 (Mar. 2008)
,
page 1791-1792.
Topik:
RNA Polymerase
Ketersediaan
Perpustakaan FK
Nomor Panggil:
S01.K.2008.03
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Recent work has shown that the RNA polymerase II enzyme pauses at a promoter-proximal site of many genes in Drosophila and mammals. This rate-limiting step occurs after recruitment and initiation of RNA polymerase II at a gene promoter. This stage in early elongation appears to be an important and broadly used target of gene regulation.
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