Should We Prescribe Statin and Aspirin for Every Diabetic Patient? Is it time for a polypill?  

Oleh:

Wienbergen, Harm ; Senges, Jochen ; Gitt, Anselm K.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Diabetes Care vol. 31 no. Sup 02 (Feb. 2008), page s222-s225.
Topik: Statin; Aspirin

Ketersediaan

Perpustakaan FK Nomor Panggil: D05.K.2008.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

An analysis of medical treatment of consecutive patients with acute coronary syndromes of the MITRA PLUS registry (Germany 2000–2002) showed that only 28% of the patients with coronary artery disease risk equivalent such as diabetes received statin therapy. Data from several large registrations support the disappointing implementation of treatment guidelines in actual clinical practice, showing that we are far away from overtreatment of patients at cardiovascular risk. Aspirin as well as statins are drugs with strong evidence of their beneficial effects, with a significant reduction of cardiovascular events and a low rate of side effects. Therefore in our opinion, a broad use of aspirin and statin treatment in diabetic patients is recommended. Based on this evidence for the benefit of aspirin as well as of statins in primary and secondary prevention in diabetic patients and decreasing compliance with an increasing number of medications, it might be time again to discuss the concept of a polypill (24), starting with a simple composition of drugs with standard dosages, especially in the setting of diabetes.

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