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ArtikelReprogrammed induced pluripotent stem cells: how suitable could they be in reproductive medicine?  
Oleh: Ensenat-Waser, Roberto ; Pellicer, Antonio ; Simon, Carlos
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 91 no. 04 (Apr. 2009), page 971-974.
Topik: reprogramming; iPS; gametes; pluripotency; germ-line; fertility
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: F02.K.2009.01
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
    Lihat Detail Induk
Isi artikelHuman embryonic stem cells have the greatest potential for regenerative and reproductive medicine; unfortunately, their full application is limited by ethical and technical problems. In order to overcome these problems and get patient specific pluripotent cells from somatic cells, the field of reprogramming has moved to the generation of induced pluripotent stem cells by overexpression of four transcription factors after viral infection of the patient's somatic cells. In the present paper we review the limitations and milestones of this technique in both regenerative and reproductive medicine.
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