Detail Large-Scale Sequencing: The Future of Genomic Sciences? Bibliografi Author: Riley, Margaret ; Buckley, Merry Topik: Genomic Sciences; Sequencing Cultivated Organisms; Cultivation--Methods & Facilities; Sequencing Coverage; Single Cell Sequencing; Unculturable Individuals; Sequencing Initiative; Ecosystems Bahasa: (EN )     Penerbit: American Academy of Microbiology     Tempat Terbit: Washington, DC    Tahun Terbit: 2009     Jenis: Research Report Fulltext: Colloqium ASM-Large_Scale_Sequencing[1].pdf (459.46KB; 2 download) [Informasi yang berkaitan dengan koleksi ini di internet] Abstract Genetic sequencing and the various molecular techniques it has enabled have revolutionized the field of microbiology. Examining and comparing the genetic sequences borne by microbes—including bacteria, archaea, viruses, and microbial eukaryotes—provides researchers insights into the processes microbes carry out, their pathogenic traits, and new ways to use microorganisms in medicine and manufacturing. Until recently, sequencing entire microbial genomes has been laborious and expensive, and the decision to sequence the genome of an organism was made on a case-by-case basis by individual researchers and funding agencies. Now, thanks to new technologies, the cost and effort of sequencing is within reach for even the smallest facilities, and the ability to sequence the genomes of a significant fraction of microbial life may be possible. The availability of numerous microbial genomes will enable unprecedented insights into microbial evolution, function, and physiology. However, the current ad hoc approach to gathering sequence data has resulted in an unbalanced and highly biased sampling of microbial diversity. A well-coordinated, large-scale effort to target the breadth and depth of microbial diversity would result in the greatest impact. The American Academy of Microbiology convened a colloquium to discuss the scientific benefits of engaging in a large-scale, taxonomically-based sequencing project. A group of individuals with expertise in microbiology, genomics, informatics, ecology, and evolution deliberated on the issues inherent in such an effort and generated a set of specific recommendations for how best to proceed. Kajian editorial A report from the AmericAn AcAdemy of microbiology; This report is based on a colloquium, sponsored by the American Academy of Microbiology, convened September 2008 in Washington, DC. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

Copyright © 2006, 2007 Unika Atma Jaya, all rights reserved