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An Experimental Approach to Genome Annotation
Bibliografi
Author:
Roberts, Richard J.
;
Karp, Peter
;
Kasif, Simon
;
Linn, Stuart
;
Buckley, Merry R.
Topik:
Gene clustering
;
tRNA modification
;
Bioinformatics
;
Enzyme Genomics Initiative
;
Functional RNAs
Bahasa:
(EN )
Penerbit:
American Society for Microbiology
Tempat Terbit:
Washington, D.C.
Tahun Terbit:
2004
Jenis:
Article - diterbitkan di jurnal ilmiah internasional
Fulltext:
ASM_GenomeAnnotation.pdf
(579.23KB;
1 download
)
[
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Abstract
The American Academy for Microbiology convened a colloquium July 19-20, 2004, in Washington, DC, to address the critical challenge of prokaryotic genome annotation and to seek ways to accelerate progress in the field. Recent advances in DNA sequencing have produced a spectacular amount of new data; literally hundreds of thousands of sequenced prokaryotic genes now await annotation. These genes can be enumerated, compared, and grouped by sequence similarity into families, yet an understanding of their biochemical functions is lacking. Genomics provides that rare opportunity in science where the boundaries of current knowledge can be clearly defined. The annotation initiative proposed in this document will extend those boundaries and will likely lead to new applications and new progress in healthcare, biodefense, energy, the environment, and agriculture. This research could also impact many commercial enterprises, such as the chemical, food and dairy industries.
Kajian editorial
A report from the American Academy of Microbiology; This report is based on a colloquium sponsored by the American Academy of Microbiology held July 19-20, 2004, in Washington, DC.
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