Dietary calcium does not exacerbate phytate inhibition of zinc absorption by women from conventional diets  

Oleh:

Hunt, Janet R ; Beiseigel, Jeannemarie M.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The American Journal of Clinical Nutrition vol. 89 no. 03 (Mar. 2009), page 839.
Topik: Vitamins; minerals; and phytochemicals

Ketersediaan

Perpustakaan FK Nomor Panggil: A07.K.2009.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background: Although calcium inhibits zinc bioavailability in rats, especially from high-phytate diets, the effect of calcium on zinc absorption by humans from practical diets remains unclear. Objective: The objective was to test the inhibitory effect of dietary calcium, in Western diets with high and low phytate content, on zinc absorption. Design: Using a 2 x 2 factorial design, zinc absorption was determined in 10 healthy women from 1-d diets with moderate and high calcium contents of 700 and 1800 mg/d and low and high phytate contents of 440 and 1800 mg/d. Absorption was measured by using extrinsically added 65Zn and subsequent whole-body scintillation counting. Results: Mean (±SE) fractional zinc absorption was 32.8 ± 2.3% from the moderate-calcium, low-phytate diet; 26.9 ± 2.4% from the moderate-calcium, high-phytate diet; 39.4 ± 2.4% from the high-calcium, low-phytate diet; and 26.2 ± 2.3% from the high-calcium, high-phytate diet. The respective values for absolute zinc absorption were 3.8 ± 0.3, 3.0 ± 0.3, 4.5 ± 0.3, and 3.2 ± 0.3 mg/d. Phytate significantly reduced fractional zinc absorption by 10 percentage points and reduced absolute zinc absorption by 25%, or 1 mg/d. Differences in dietary calcium did not affect zinc absorption, regardless of a high or low dietary phytate content. Conclusions: In healthy women consuming 1-d menus of ordinary foods (some fortified with calcium), dietary phytate reduces zinc absorption, but calcium does not impair zinc absorption, regardless of whether dietary phytate is low or high.

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