Effects of lupin kernel flour–enriched bread on blood pressure: a controlled intervention study  

Oleh:

Lee, Ya P ; Mori, Trevor A ; Puddey, Ian B ; Sipsas, Sofia

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The American Journal of Clinical Nutrition vol. 89 no. 03 (Mar. 2009), page 766.
Topik: Cardiovascular disease risk

Ketersediaan

Perpustakaan FK Nomor Panggil: A07.K.2009.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Background: Available data suggest that substitution of refined carbohydrate in the diet with protein and fiber may benefit blood pressure. Lupin kernel flour is high in protein and fiber and low in carbohydrate. Objective: Our objective was to determine the effects on blood pressure of a diet moderately higher in dietary protein and fiber achieved by substituting lupin kernel flour for wheat flour in bread. Design: Overweight and obese men and women (n = 88) were recruited to a 16-wk parallel-design study. Participants were randomly assigned to replace 15–20% of their usual daily energy intake with white bread (control) or lupin kernel flour–enriched bread (lupin). Measurements, including 24-h ambulatory blood pressure, were taken at baseline and 16 wk. Results: Seventy-four participants (37 per group) completed the intervention. Baseline mean (±SD) systolic/diastolic blood pressures were 122.1 ± 9.6/70.8 ± 7.2 mm Hg (control) and 120.1 ± 9.5/71.2 ± 5.9 mm Hg (lupin). For lupin relative to control, the estimated mean (95% CI) net differences in protein, fiber, and carbohydrate intakes during the intervention were 13.7 g/d (95% CI: 2.3, 25.0 g/d), 12.5 g/d (95% CI: 8.8, 16.2 g/d), and –19.9 g/d (95% CI: –45.2, 5.5 g/d), respectively. Differences in systolic blood pressure, diastolic blood pressure, pulse pressure, and heart rate were –3.0 mm Hg (95% CI: –5.6, –0.3 mm Hg; P = 0.03), 0.6 mm Hg (95% CI: –1.0, 2.2 mm Hg; P = 0.47), –3.5 mm Hg (95% CI: –5.3, –1.8 mm Hg; P < 0.001), and 0.0 beats/min (95% CI: –1.7, 1.7 beats/min; P = 0.99), respectively. Conclusions: Increasing protein and fiber in bread with lupin kernel flour may be a simple dietary approach to help reduce blood pressure and cardiovascular risk.

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