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Terapi medikamentosa diabetes mellitus tipe 2 terkini
Bibliografi
Author:
WIDYAMISHALOCA, MARIA
;
ROSALI, ALEXANDER
;
Makimian, S.Robby
(Advisor);
Iryaningrum, Maria Riastuti
(Advisor)
Topik:
diabetes mellitus type 2
;
kencing manis
;
penyakit gula
Bahasa:
(ID )
Penerbit:
Fakultas Kedokteran Unika Atma Jaya
Tempat Terbit:
Jakarta Utara
Tahun Terbit:
2009
Jenis:
Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Ketersediaan
Perpustakaan FK
Nomor Panggil:
KTI-FK-51
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Abstract
Diabetes Mellitus (DM) is a group of metabolic diseases with characteristic hyperglycemia that occurs due to the abnormal secretion of insulin, and/or insulin resistance. DM is divided into two major classifications of the DM type 1 and type 2 Diabetes. DM type 1 occurs in the absence of insulin. While the type 2 Diabetes occurs because insulin is not used as expected (insulin resistance). Although the prevalence of DM type 1 and type 2 increases worldwide, the prevalence of type 2 Diabetes increased more rapidly than type 1. This is because the increase in obesity and reduced activity that occurs in society and this is a risk factor for type 2 Diabetes. Both the research to find the appropriate and accurate address to prevent complications in people with type 2 Diabetes. Studies conducted primarily in the search for effective medical treatment in the blood glucose control. There are two categories of drugs most recent Glucagon-like group Antidiabetik Peptide-1 Receptor agonist (Agonist GLP - 1) and the Dipeptidyl-peptidase-IV group Inhibitors (inhibitors DPP-IV). The works of GLP-1 Agonists are the same as inkretin GLP-1, a hormone that produced by the pancreas to stimulate insulin secretion. Meanwhile, DPP-IV Inhibitors work by slowing the inactivation inkretin hormone GLP-1 and GIP (Glucose-dependent Insulinotropic Polypeptide), so the hormone can stimulate insulin inkretin spending again. The use of the lastest oral antidiabetic medication for people with Diabetes type 2 needs more further validity test, because although drugs proved controlling blood sugar type 2 Diabetes, but not yet published results of research on the bad effects occur in the use of new medicines.
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