Detail In Vitro Anti-biofilm Activity of Macelignan isolated from Myristica fragrans Houtt. Against Oral Primary Colonizer Bacteria (Phytoteraphy Research, Vol. 22, 2008) Bibliografi Author: Yanti ; Hwang, Jae-Kwan ; Kyu-Hoi, Kim ; Rukayadi, Yaya Topik: Anti-biofilm Activity; Macelignan; Mvristica Fragrans Houtt; Oral Bacteria Bahasa: (EN )     Penerbit: Wiley Interscience     Tempat Terbit: New York    Tahun Terbit: 2010     Jenis: Article - diterbitkan di jurnal ilmiah internasional Fulltext: In Vitro Anti-biofilm Activity of Macelignan Isolated from Myristica Fragrans Houtt.pdf (2.53MB; 4 download) Abstract In early denial plaque formation, oral primary colonizers such as Streptococcus mutans. Streptococcus sanguis and Actinomyces viscosus are initially attached to the pellicle-coaled tooth surface to form a biofilm. The study aimed to determine the efficacy of macelignan. isolated from nutmeg (Myristica fragrans Houtt). In removing each single oral primary biofilm in vitro on a polystyrene 96-well microtiter plate. Four biofilm growth phases (4, 12, 20 and 24 h) were evaluated in this study after treatment with macelignan at various concentrations (0.2, 2 and 10 µg/mL) and exposure times (5. 10 and 30 min). Anti-biofilm activity of macelignan was measured as the percentage of the remaining biofilm absorbance after macelignan treatment in comparison with the untreated control. At 24 h of Biofilm growth, S. mutatis. A. viscosus and .V. sanguis biofilms were reduced by up to 30%, 30% and 38%, respectively, after treatment with 10µg/mL macelignan for 5 min. Increasing the treatment time to 30 min resulted in a reduction of more than 50% of each of the single primary biofilms. The results indicate that macelignan is a potent natural anti-biofilm agent against oral primary colonizers. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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