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Genetic programming based DNA microarray analysis for classification of tumor tissues
Bibliografi
Author:
Rosskopf, Michael
;
Feldkamp, Udo
;
Banzhaf, W.
Topik:
DNA Microarray
Bahasa:
(EN )
Penerbit:
RML Technologies Inc
Tempat Terbit:
USA
Tahun Terbit:
2004
Jenis:
Article - diterbitkan di jurnal ilmiah internasional
Fulltext:
Genetics Programming Based DNA Microarray(1).pdf
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Abstract
Gene expression data gained from DNA- microarrays have been examined with several approaches during the last few years. In many cases statistical methods or learning techniques were used to classify the origin or state of tissues the gene samples have been taken from. In this article we present a Genetic Programming (GP) approach to this problem. We trained classifiers on four different public cancer data sets, including multi-class sets, using the general purpose GP-system DISCIPULUS. In a preprocessing step a subset of all sampled genes has to be selected to get smaller data sets and to avoid overfitting. We examined several different statistical measures on their applicability to this selection. The results indicate that GP is an appropriate method for gene expression data analysis.
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