Probabilistic Cost-Effectiveness Analysis Of HIV Prevention: Comparing A Bayesian Approach With Traditional Deterministic Sensitivity Analysis  

Oleh:

Johnson-Masotti, Ana P. ; Laud, Purushottam W. ; Hoffmann, Raymond G. ; Hayat, Matthew J. ; Pinkerton, Steven D.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Evaluation Review vol. 25 no. 4 (Aug. 2001), page 474-502.
Fulltext: 474.pdf (282.78KB)

Isi artikel

In cost-effectiveness analysis, the incremental cost-effectiveness ratio is used to measure economic efficiency of a new intervention, relative to an existing one. However, costs and effects are seldom known with certainty. Uncertainty arises from two main sources: uncertainty regarding correct values of intervention-related parameters and uncertainty associated with sampling variation. Recently, attention has focused on Bayesian techniques for quantifying uncertainty. We computed the Bayesian-based 95% credible interval estimates of the incremental cost-effectiveness ratio of several related HIV prevention interventions and compared these results with univariate sensitivity analyses. The conclusions were comparable, even though the probabilistic technique provided additional information.

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