Platelets, Petechiae, and Preservation of the Vascular Wall  

Oleh:

Nachman, Ralph L. ; Rafii, Shahin

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 359 no. 12 (Sep. 2008), page 1261.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2008.05 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Platelets help to maintain blood circulation by controlling hemorrhage after an injury to the blood-vessel wall that causes physical or biochemical disruption of the endothelium. The development of an activated platelet plug at the site of trauma seals the vascular lesion and brings about hemostasis. The membrane-oriented processes of subendothelial adhesion of platelets, granule release, cohesion, aggregation, and plug stabilization involve several well-characterized ligand–receptor interactions1 and will not be discussed further in this review. Instead, we will focus on other functional contacts between platelets and endothelial cells. The most important of these is the maintenance of vascular integrity by the . . .

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