Pengaruh Pemberian Kontras Media Non Ionik Low Osmolar Intra Vena Terhadap Kadar Cystatin-C Serum pada Oryctalagus Cuniculus  

Oleh:

Bintoro, Ariyo Sakso ; Soetojo ; Soebadi, Doddy M. ; Retnowati, Endang ; Widodo JP.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Jurnal Urologi Indonesia (Indonesian Journal of Urology) vol. 15 no. 02 (Jul. 2008), page 49.
Topik: Cystatin-C serum; low osmolar non ionic contrast media; Oryctalagus cuniculus

Ketersediaan

Perpustakaan FK Nomor Panggil: J33.K.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective: To measure effects of low osmolar non ionic contrast media on cystatin-C serum levels on different days after administration. Material and method: twenty-two Oryctalagus cuniculus were divided into two groups of 11 subjects, each subject receiving intravenous injection of low osmolar non ionic contrast or a placebo solution (NaCl 0,9%). Cystatin-C serum levels of each subjects were measured before injection, on days 1,3,7,10. Cystatin-C serum levels were determined with a sandwich ELISA method. Statistical analysis was performed with t-test. Results:Mean cystatin-C serum levels before injection was 0,00337+-0,00101 mg/L. Means from days 1,3,7 and 10 after injection were 0,00498+-0,00153 mg/L; 0,00565 +- 0,00247 mg/L; 0,00468+- 0,00157, and 0,00339+-0,00188 mg/L respectively. Conclusion: Increase in serum cystatin-C levels on days 1,3, and 7 was significant. On the 10th day no significant escalation was observed. Compared to the control group, there were significant differences in serum cystatin-C increase on days 1 and 3 in the intervention group, but no significant differences 7 and 10 days after injection.

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