Detail Remodeling of A Collagenous Tissue at Fixed Lengths   Oleh:  Humphrey, J. D. Jenis: Article from Bulletin/Magazine Dalam koleksi: Journal of Biomechanical Engineering vol. 121 no. 6 (1999), page 591-597. Topik: TISSUES; collagenous tissue; fixed lengths Ketersediaan Perpustakaan Pusat (Semanggi) Nomor Panggil: JJ52.1 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada     Lihat Detail Induk Isi artikel Mature tissues can often adapt to changes in their chemical, mechanical, or thermal environment. For example, in response to sustained increases or decreases in mechanical loads, some tissues grow and remodel so as to restore the stress or strain to its homeostatic state. Whereas most previous work addresses gross descriptors of tissue growth, this paper introduces a possible cell - mediated mechanism by which remodeling may occur in a soft connective tissue - that the kinetics of collagen deposition and degradation is similar regardless of the configuration of the body at which it occurs. The proposed theoretical framework applies to three - dimensional settings, but it is illustrated by focusing on the remodeling of a uniaxial collagenous tissue that is maintained at a fixed length for an extended period. It is shown that qualitative features expected of such remodeling (e. g., an increased compliance and increased stress-free length when remodeling occurs at an extended length) are easily realized. Growth and remodeling are complex phenomena, however, and are likely accomplished via multiple complementary mechanisms. There is a need, therefore, to identify other candidate mechanisms and, of course, to collect experimental data suitable for testing and refining the possible theories. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

Copyright © 2006, 2007 Unika Atma Jaya, all rights reserved