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BukuMathematical Modeling of the HOG Pathway in Saccharomyces Cerevisiae
Bibliografi
Author: Bayati, Basil
Topik: HOG pathway; Saccharomyces cerevisiae; Cells
Bahasa: (EN )    
Penerbit: Master’s Thesis in Mathematical Statistics and Bioinformatics at Chalmers University of Technology and Göteborg University     Tempat Terbit: Göteborg    Tahun Terbit: 2006    
Jenis: Theses - Master Thesis
Fulltext: 1_Mathematical Modeling of the HOG Pathway in Saccharomyces Cerevisiae.pdf (1.48MB; 1 download)
Abstract
Numerical solutions of reaction-diffusion partial differential equations are obtained for modeling protein concentrations, taking into account the physical structure of biological cells. An Immersed Interface Method is used for the numerical solution. The biochemical model is the HOG pathway signaling cascade in Saccharomyces cerevisiae, effectively modeling both time and three dimensional space. Perturbations to the reaction rates in the biochem¬ical system are investigated, along with their corresponding effects regarding the spatial distribution of proteins. A model elucidating the relationship between the Hogl and Rck2 proteins is analyzed and discussed.
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