The effects of docosahexaenoic acid-rich fish oil on behavior, school attendance rate and malaria infection in school children – a double-blind, randomized, placebo-controlled trial in Lampung,Indonesia  

Oleh:

Hamazaki, Kei ; Syafruddin, Din ; Tunru, Insan S ; Azwir, Marina F ; Asih, Puji BS ; Sawazaki, Shigeki ; Hamazaki, Tomohito

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Asia Pacific Journal of Clinical Nutrition (keterangan: ada di Proquest) vol. 17 no. 02 (2008), page 258.
Topik: behavior; fatty acid composition of red blood cells; fish oil; intervention study; malaria; school attendance rate

Ketersediaan

Perpustakaan FK Nomor Panggil: A27.K.2008.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background: There are only a very limited number of reports of intervention studies on the effects of fish oil on behavior in normal school children. Objective: To observe the effects of fish oil on behavior and school attendance rates in school children. Design: Fourth to sixth graders (mostly 9-12 years of age) of an elementary school in Lampung Province, Indonesia, were randomly divided into either a docosahexaenoic acid (DHA) group (n=116) or a control group (n=117) in a double-blind manner. The subjects in the DHA group took 6 fish oil capsules per day (0.65g DHA and 0.10g eicosapentaenoic acid (EPA)/day) for 3 months. Controls took soybean oil capsules. Two questionnaires were administered and blood was taken at the start and end of the study. Two questionnaires were administered at the start and end of the study: Hostility-Aggression Questionnaire for Children (HAQ-C) and Barratt Impulsiveness Scale, version 11 (BIS-11), for measurement of aggression and impulsivity, respectively. Attendance was recorded during the study period. Outcomes: The concentrations of DHA and EPA in the phospholipid fraction in red blood cells were significantly increased in the DHA group. Behavior checked with HAQ-C or BIS-11 did not show any differences between groups. However, the odds ratio of inability to attend school regularly during the study period was 0.40 (95%CI: 0.23-0.71) in the DHA group compared with controls (p=0.002). Conclusions: DHA-rich fish oil may improve the school attendance rate of children in Lampung, Indonesia

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