HIV Integrase Inhibitors — Out of the Pipeline and into the Clinic  

Oleh:

Havlir, Diane V.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 359 no. 04 (Jul. 2008), page 416.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2008.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Human immunodeficiency virus (HIV) infection has been transformed over the past two decades from a fatal to a chronic disease, because of combination antiretroviral therapy — a medical triumph.1 However, HIV has proven to be a masterful escape artist with regard to the pharmacologic agents strategically deployed to block its replication, and the counterpoint to the antiretroviral success story is one of drug resistance and toxicity. For a sizable number of patients who have developed or acquired highly drug-resistant HIV, suffering the ill effects of HIV disease is either a reality or a looming threat. In most patients with highly . . .

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