Pharmacogenomics and Drug Toxicity  

Oleh:

Nakamura, Yusuke

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 359 no. 08 (Aug. 2008), page 856.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2008.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

In the United States alone, it is estimated that adverse drug reactions affect nearly 2 million patients and kill about 100,000 people each year.1 Adverse drug reactions are often classified into two groups. The first group can be explained by the mode of action of the therapeutic drug. Examples of adverse drug reactions in this group include hypoglycemia induced by diabetic drugs, leukopenia induced by cytotoxic anticancer drugs, and bleeding induced by warfarin, an oral anticoagulant. The phenotypes of the second group are not explained by the mode of action of the drug. Examples in this group are toxic epidermal . . .

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