Effects of an Attachment-Based Intervention on Daily Cortisol Moderated by Dopamine Receptor D4: A Randomized Control Trial on 1- to 3-year-olds Screened for Externalizing Behavior  

Oleh:

Bakermans-Kranenburg, Marian J. ; Ijzendoorn, Marinus H. Van ; Mesman, Judi ; Alink, Lenneke R. A. ; Juffer, Femmie

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Development and Psychopathology vol. 20 no. 3 (2008), page 805-820.
Topik: Daily Cortisol Moderated; Dopamine Receptor D4; Externalizing Behavior; VIPP-SD Program
Fulltext: DD21V20N3P805.pdf (227.03KB)

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: DD21.15 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The effect of the Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP-SD) on daily cortisol production was tested in a randomized controlled trial with 130 families with 1- to 3-year-old children screened for their relatively high levels of externalizing behavior. Six 1.5-hr intervention sessions focusing on maternal sensitivity and discipline were conducted with individual families at their homes. Children in the intervention group showed lower cortisol levels, with a moderating role of the dopamine receptor D4 (DRD4) VNTR exon III polymorphism. The VIPP-SD program proved to be effective in decreasing daily cortisol production in children with the DRD4 7-repeat allele, but not in children without the DRD4-7 repeat allele. Our findings indicate that children are differentially susceptible to intervention effects dependent on the presence of the 7-repeat DRD4 allele.

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