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Designed PCL Nanofibers Fabricated Using a Modified Electrohydrodynamic Process for Tissue Engineering
Oleh:
GeunHyung Kim
;
WanDoo Kim
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
Journal of Manufacturing Science and Engineering vol. 130 no. 2 (Apr. 2008)
,
page 021006.
Topik:
Electrohydrodynamic Process
;
Tissue Engineering
Ketersediaan
Perpustakaan Pusat (Semanggi)
Nomor Panggil:
JJ93.11
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
An ideal scaffold should have good mechanical properties and provide a biologically functional implant site. Considering their large surface area, high porosity, and good interconnectivity of pores, electrospun micro-/nanofibers have good potential as biomimic scaffolds. In this study, various poly(-carprolactone) webs consisting of uniaxially oriented micro-/nanofibers were produced using an electrohydrodynamic process (electrospinning) with a conical electrode and two-axis collector. The oriented fibrous web showed mechanical orthotropic properties, which might be important for designing engineering scaffolds that mimic natural tissues, such as a blood vessel or ligament, which have orthotropic mechanical properties. In addition, the fabricated mats, which were electrospun using computer-assisted design, had good hydrophilic and good cellular behavior compared to a random fiber mat.
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