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The basis for choice reaction time slowing in Alzheimer's disease
Oleh:
Carson, Kathryn
;
Gordon, Barry
Jenis:
Article from Bulletin/Magazine
Dalam koleksi:
Brain and Cognition vol. 13 no. 2 (Jul. 1990)
,
page 148-166.
Ketersediaan
Perpustakaan PKBB
Nomor Panggil:
405/BAC/13
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Isi artikel
Slowed reaction time has been suggested as an early feature of Alzheimer's disease (AD), but the basis for this slowing has not been established. Patients with mild AD were compared with controls on a choice reaction time task, both cued (CCRT) and uncued (CRT). Initial and I-year follow up data were analyzed both as mean reaction times and as parameters of a fitted two-component quantitative model (the ex-Gaussian model). Slowing of CRT proved to be a sensitive test for AD. Slowing was due to changes in both the sensory/motor and the decisional components of the CRT model. However, these changes were found in both AD and slower, older controls. The modeling of CRT in AD is discussed. (!:) 1990 Academic Press, Inc.
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