Cardiac Plasticity  

Oleh:

Hill, Joseph A. ; Olson, Eric N.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 358 no. 13 (Mar. 2008), page 1370.
Topik: Mechanisms of Disease

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2008.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

The heart is capable of remodeling in response to environmental demands, and a variety of stimuli can induce it to grow or shrink (Figure 1). Exercise, pregnancy, and postnatal growth promote physiologic growth of the heart, whereas neurohumoral activation, hypertension, and myocardial injury can cause pathologic hypertrophic growth. In contrast to physiologic growth, hypertrophic growth can increase the risk of heart failure and malignant arrhythmia. Atrophy of the heart is a complication of protracted bed rest, prolonged weightlessness during space travel, and mechanical unloading with a ventricular assist device.

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