Reduce, Recycle, Reuse — Iodotyrosine Deiodinase in Thyroid Iodide Metabolism  

Oleh:

Kopp, Peter A.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 358 no. 17 (Apr. 2008), page 1856.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2008.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Thyroid hormones are essential for normal brain development, growth, and metabolism. Their synthesis is dependent on a normally developed thyroid gland, an adequate nutritional intake of iodide, and a series of biochemical steps to organify iodide.1 Iodide is scarce in most environments. Despite important progress in eradicating iodine deficiency disorders, which lead to the development of endemic goiter and are associated with various degrees of mental retardation, iodine deficiency remains a major public health issue.2 The first step in thyroid-hormone biosynthesis consists of iodide uptake at the basolateral membrane by the sodium–iodide symporter (Figure 1). Iodide is then . .

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali