Isolasi dan Elusidasi Struktur Senyawa Lignan dan asam Lemak dari ekstrak daging buah Phaleria Macrocarpa  

Oleh:

Lisdawati, Vivi ; Wiryowidagdo, Sumali ; Kardono, L. Broto S.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Buletin Penelitian Kesehatan: Bulletin of Health Studies vol. 35 no. 03 (2007), page 115.
Topik: FTIR; H-RMI; H; H-COSY; TOCSY dan NOESY RMI; LC-MS; lignan; P. macrocarpa; Thememlaeaceae; UV-Vis; 5-[4(4-methoxy-phenyl)-tetrahydro-furo[3; 4-c] furan-1-yl]-benzene-1; 2; -triol

Ketersediaan

Perpustakaan FK Nomor Panggil: B18.K.2003-2008.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Application of an in vitro anticancer bioassays were guided fractionation of bioactive higher plant and extracts led to the isolation of a variety natural products with potential anticancer activity. Presented herein are interesting struktural features of the ethyl acetate mesocarp active fraction of phaleria macrocarpa, fam. Thymelaeceae. these fractions werw fractionated by using open column silica gel chromatography following identification, resulted in the isolation of known lignan 5-[4(4-Methoxy-phenyl)-tetrahydrofuro[3,4-c] furan- 1-yl]-benzene-1,2,3-triol, and also unidentified fatty acid compuond. their structures indentification were based on chemical and spectroscopic methods such as ultraviolet-visible (UV-Vis) spevtra data, fourier transform infra red (FTIR) spectrometric, liquid chomatography-mass spectrometry (LC-MS), the proton nuclear magnetic resonance spectral data H-RMI and combination of H, H-COSY, TOCSY and NOESY RMI. using taxonomy chemotaxonomy Dahlgren and Conqrist system approached indicated that the lignan compound have cytotoxic activity.

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