Pemantauan Efikasi klorokuin untuk pengobatan Malaria Falciparum Ringan Di Daerah High Case Incidence (HCI) Banjarnegara, jawa Tengah  

Oleh:

Tuti, Sekar ; Dewi, Rita Marleta ; Kristi, Natalia ; Gunawan, Ari

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Buletin Penelitian Kesehatan: Bulletin of Health Studies vol. 35 no. 03 (2007), page 97.

Ketersediaan

Perpustakaan FK Nomor Panggil: B18.K.2003-2008.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Malaria remains a public health problem in several areas of Banjarnegara regency. Drug resistance or treatment failure is one of the main obstacles in controlling the disease in this area. To support The Malaria Control Program, since July 2001 up to June 2002 monitoring of the efficacy of chloroquine as a first line drug for uncomplicated falciparum malaria treatment was conducted in Two Health Centers (Banjarmangu I and Banjarmangu II). it was found that only 37.21 % (16/43) cases showed ACPR (Adequate Clinical and Parasitoplogical Responses), 6.98% (3/43) caseswith ETF (early treatment Failure) and 55.81% (24/43) cases considered as LTF (late treatment Failure). the over all treatment failure was happened on day-1. Seven patient had no temperature increase since day-0 (below 37.5 0 C). while the parasite clearence time (PCT) on day-2 was 43.75 % and on day-3 was 50%. it was concluded that chloroquine treatment for uncomplicated Falciparum malaria in HCL area of Banjarnegara regency showed: (1), High proportion of treatment failure (62.79%) and high cumulative incidence of treatment failure within 28 days (62.60%) as well. (2) there was a proportion increase of treatment failure from 28.57% to 62.79%, during 1989-2002.

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