Optimal Cut Points of Waist Circumference for the Clinical Diagnosis of Metabolic Syndrome in the Japanese Population  

Oleh:

Matoba, Yuka ; Inoguchi, Toyoshi ; Nasu, Shigeru ; Suzuki, Shizu ; and Others

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Diabetes Care vol. 31 no. 03 (Mar. 2008), page 590.
Topik: IDF; International Diabetes Federation ; IMT; intima-media thickness ; ROC; receiver operating characteristic

Ketersediaan

Perpustakaan FK Nomor Panggil: D05.K.2008.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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INTRODUCTION In 2005, the International Diabetes Federation (IDF) and the Japanese Committee for the Diagnostic Criteria of Metabolic Syndrome (Japanese definition) proposed metabolic syndrome definitions for the Japanese population (1,2). Both definitions included waist circumference as an essential component and adopted cut points of 85 cm for men and 90 cm for women based on the relationship between waist circumference and visceral fat area by computed tomography (3). However, those cut points have been in dispute because of their suboptimal sensitivity and specificity (4–6). Recently, the IDF proposed common cut points for the whole Asian population including the Japanese: 90 cm for men and 80 cm for women (7). In this study, we investigated optimal waist cut points to identify subjects with multiple risk factors in the Japanese population and verified the cut points to predict carotid intima-media thickening in metabolic syndrome subjects as a surrogate marker of early atherosclerosis and cardiovascular disease (8–10). RESEARCH DESIGN AND METHODS We reviewed cross-sectional data from 1,658 men and 1,116 women (aged 48.8 ± 9.8 and 46.8 ± 10.4 years, respectively) who had annual medical checkup services provided by their employers. The medical checkup took place from May 2005 to November 2006 at the Human Dry Dock Center Wellness in Fukuoka, Japan. Subjects on antihypertensive and/or antidiabetic medications were included as individuals with hypertension and/or diabetes, respectively. We excluded 158 subjects on medications for dyslipidemia because we were unable to determine whether . . .

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