Diet and risk factors for age-related maculopathy  

Oleh:

O'Connell, Eamonn D. ; Nolan, John M. ; Stack, Jim ; Greenberg, David ; Kyle, Janet ; Maddock, LeighAnne ; Beatty, Stephen

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The American Journal of Clinical Nutrition vol. 87 no. 03 (Mar. 2008), page 712.
Topik: Age-related macular degeneration ; age-related maculopathy ; antioxidants ; lutein ; n–3 fatty acids ; zeaxanthin

Ketersediaan

Perpustakaan FK Nomor Panggil: A07.K.2008.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Background: Evidence continues to accumulate that oxidative stress is etiologically important in the pathogenesis of age-related maculopathy (ARM) and that appropriate antioxidants of dietary origin may protect against this condition. Objective: Risk factors for ARM may be classed as established or putative. We report a study designed to investigate whether such risk factors are associated with a dietary lack of antioxidants relevant to retinal health. Design: Dietary, anthropometric, and sociodemographic details relating to 828 healthy Irish subjects aged 20–60 y were recorded in a cross-sectional fashion and analyzed for associations between risk factors for ARM and dietary intake of relevant nutrients. Results: Of the established risk factors for ARM, increasing age was associated with a relative lack of dietary zeaxanthin (P < 0.05) and tobacco use with a relative lack of dietary vitamin C (P < 0.05). Of the putative risk factors for ARM, alcohol consumption was associated with a relative lack of dietary -linoleic acid (P < 0.05), and female sex was associated with a relative lack of dietary zinc (P < 0.05). Conclusions: We showed that several variables related to risk for ARM are associated with a relative dietary lack of key nutrients. Our finding that age, the most important and universal risk factor for ARM, is associated with a relative lack of dietary zeaxanthin, is an important finding that warrants further investigation.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali