Effect of Circardian Rhythm Changes on Innate Immunity Response  

Oleh:

Martiana, Tri

Jenis: Article from Journal - ilmiah nasional
Dalam koleksi: The Indonesian Journal of Public Health vol. 04 no. 02 (Nov. 2007), page 48.
Topik: circardian rhythm; night shift; cortisol; psychoneuroimmunology; immune response

Ketersediaan

Perpustakaan FK Nomor Panggil: I10.K.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The adaptation failure of circardian rhythm cause workers. The research aims to prove that the work stress will affect the innate immunity, by the concept of psychoneuroimmunology. THe research was done by using quasi-experimental research design and similar working unit workers who have never been in night shift work as control. Samples were selected among male workers, unmarried, 20-25 years old with good health status and no psychological disturbances. Responses of cortisol hormone was used as stress indicator, and cellular response of monocyte, lymphocyte, neuthrophyl, and natural killer (NK) cell were used as immune response indicators. Data were collected during 5(five) working days. This study shows that cortisol hormone and neuthrophyl cell are the important indicators in the circardian rhythm among workers. Two profiles appear in the group studied. The first is considered adaptive to circardian rhythm. The second group, unadaptive group, as a group where the work stress occurs and this is showed by the high of cortisol response with low response of neuthrophyl cell. Circardian rhytm canges can play as a stressor for rotating shift worker.

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