| Nuclear factor kappa B [NF-kB] is an ubiquitous rapid response transcription factor in cells involved in immune and inflammatory reactions, and exerts its effect by expressing cytokines, chemokines, cell adhesion molecules, growth factors, and immunoreceptors. In this manner, NF-kB contributes to immunologically mediated diseases such as allograft rejection, rheumatoid arthritis, and bronchial asthma. ... (more) |