Detail Arabidopsis CLV3 Peptide Directly Binds CLV1 Ectodomain   Oleh:  Ogawa, Mari ; Shinohara, Hidefumi ; Sakagami, Youji ; Matsubayashi, Yoshikatsu Jenis: Article from Bulletin/Magazine Dalam koleksi: SCIENCE (keterangan: ada di Proquest) vol. 319 no. 5861 (Jan. 2008), page 294. Ketersediaan Perpustakaan FK Nomor Panggil: S01.K.2008.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada     Lihat Detail Induk Isi artikel CLV1, which encodes a leucine-rich repeat receptor kinase, and CLV3, which encodes a secreted peptide, function in the same genetic pathway to maintain stem cell populations in Arabidopsis shoot apical meristem. Here, we show biochemical evidence, by ligand binding assay and photoaffinity labeling, that the CLV3 peptide directly binds the CLV1 ectodomain with a dissociation constant of 17.5 nM. The CLV1 ectodomain also interacts with the structurally related CLE peptides, with distinct affinities depending on the specific amino acid sequence. Our results provide direct evidence that CLV3 and CLV1 function as a ligand-receptor pair involved in stem cell maintenance. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

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