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Computed Tomography–Based Radiation Therapy of Ovarian Remnants for Symptomatic Persistent Endometriosis
Oleh:
Haglund, Karl E.
;
Viswanathan, Akila N.
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
Obstetrics and Gynecology vol. 111 no. 02 (Feb. 2008)
,
page 579.
Ketersediaan
Perpustakaan FK
Nomor Panggil:
O01.K.2008.01
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
BACKGROUND: Endometriosis, a major cause of pelvic pain in women, is driven by estrogen. Ovarian remnant irradiation may alleviate pelvic pain by eliminating estrogen production in appropriately selected women with endometriosis. CASE: Three patients with endometriosis causing incapacitating pelvic pain received 3D-imaging–based external beam radiation to doses of 1,500 to 2,100 cGy. All had pre-irradiation premenopausal follicle stimulating hormone levels and imaging evidence of ovarian remnants. None were candidates for further medical or surgical interventions. By 3 months after radiation, follicle stimulating hormone levels reached postmenopausal levels in all three patients, with complete resolution of the severe pelvic pain. CONCLUSION: Radiation therapy effectively induced menopause and relieved refractory pain from endometriosis. Careful selection of patients is necessary, given the potential for an increased long-term risk of radiation-related complications.
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