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ArtikelAnal ulceration induced by nicorandil  
Oleh: Akbar, Fayyaz ; Maw, Andrew ; Bhowmick, Arnab
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: British Medical Journal (keterangan: ada di Proquest) vol. 335 no. 7626 (Nov. 2007), page 936.
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: B16.K.2007.01
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
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Isi artikelNicorandil is widely used to treat angina, particularly in patients with severe coronary vessel disease. Anal ulceration is a recognised side effect of its use,1 2 but the association between the two is not widely appreciated. We want to alert primary care practitioners, general physicians, dermatologists, cardiologists, and surgeons who may encounter such cases of the importance of this association. Case report A 73 year old man was referred to our department with a one year history of rectal bleeding, mucus discharge, and anal pain. Associated conditions included diabetes mellitus, hypertension, hypercholesterolaemia, and severe ischaemic heart disease. Despite two previous coronary artery bypass operations, he continued to have angina. His medication included aspirin, atenolol, amlodipine, simvastatin, allopurinol, gliclazide, and 30 mg nicorandil twice a day. Initial assessment found a small posterior anal fissure and anal skin tags. For investigation of the bleeding, he underwent a rigid sigmoidoscopy and a barium enema, results of . . .
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