Anabolic Therapy in Glucocorticoid-Induced Osteoporosis  

Oleh:

Sambrook, Philip N.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 357 no. 20 (Nov. 2007), page 2084.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2007.06 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Glucocorticoids are widely used because of their important and efficacious immunosuppressive and antiinflammatory properties. However, glucocorticoid-induced osteoporosis, a major adverse event, is a common clinical problem. The risk of osteoporosis with glucocorticoid therapy remains unclear, but the disease has been reported to occur in up to 50% of patients who require long-term therapy. Fractures can occur rapidly, with a predilection for sites that are rich in trabecular bone, such as the spine and ribs. There are few prospective epidemiologic data regarding fractures and their association with glucocorticoid-induced bone loss, but a large, retrospective cohort study of patients receiving glucocorticoids who . . .

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