Changes in Vigorous Physical Activity and Incident Diabetes in Male Runners  

Oleh:

Williams, Paul T.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Diabetes Care vol. 30 no. 11 (Nov. 2007), page 2838.

Ketersediaan

Perpustakaan FK Nomor Panggil: D05.K.2007.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

OBJECTIVE—We examined the relationship between changes in reported vigorous exercise and self-reported physician-diagnosed diabetes in 25,988 active men. RESEARCH DESIGN AND METHODS—The dose-response relationship between changes in reported vigorous exercise (running distance, change in kilometers per week) and self-reported physician-diagnosed diabetes was followed prospectively for 7.8 ± 1.8 years (means ± SD). RESULTS—Logistic regression analyses showed that the log odds for diabetes declined significantly in relation to men's change in running distance (coefficient ± SE: –0.012 ± 0.004, P < 0.01), which remained significant when adjusted for BMI (–0.018 ± 0.003, P < 0.0001). The decline in the log odds for diabetes was related to the distance run at the end of follow-up when adjusted for baseline distance, with (–0.024 ± 0.005, P < 0.0001) or without (–0.027 ± 0.005, P < 0.0001) adjustment for BMI. Baseline distance was unrelated to diabetes incidence when adjusted for the distance at the end of follow-up. Compared with men who ran <8 km/week at the end of follow-up, incidence rates in those who ran 8 km/week were 95% lower between 35 and 44 years of age (P < 0.0001), 92% lower between 45 and 54 (P < 0.0001), 87% lower between 55 and 64 (P < 0.0001), and 46% lower between 65 and 75 (P = 0.30). For the subset of 6,208 men who maintained the same running distance during follow-up (±5 km/week), the log odds for diabetes declined with weekly distance run (–0.024 ± 0.010, P = 0.02) but not when adjusted for BMI (–0.005 ± 0.010, P = 0.65). CONCLUSIONS—Vigorous exercise significantly reduces diabetes incidence, due in part to the prevention of age-related weight gain and in part to other exercise effects.

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