Phytoestrogens as Promoters and Protectors of Breast Cancer  

Oleh:

Liben, Paulus

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Majalah Ilmu Faal Indonesia vol. 06 no. 02 (Feb. 2007), page 74.
Topik: phytoestrogens; breast cancer

Ketersediaan

Perpustakaan FK Nomor Panggil: M07.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

There is paradox concerning the epidemiology of breast cancer and the dietary intake phytoestrogens that bind weakly to oestrogens receptors and initiate oestrogen-depent transcription. Indeed, their weak oestrogenicity has been used to advantage by herbalist medicine to promote soy product as a natural alternative to conventional hormone replacement therapy (HRT). Such usage could increase in light of recent evidence that long term HRT usage may be associated with an increase risk of breast cancer. So, are phytoestrogens safe as a natural alternative to HRT and could they be promoters or protectors of breast cancer? If they are promoters, then we must assume tahat it is due to their oestrogenic effect. If they are protector, then other actions of phytoestrogens, including their ability to inhibit enzymes that are responsible for converting androgens and weak oestrogens into oestradiol, must be considered.

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